6MIM

Crystal structure of AF9 YEATS domain Y78W mutant in complex with histone H3K9cr

Summary for 6MIM

Entry DOI	10.2210/pdb6mim/pdb
Descriptor	Protein AF-9, Histone H3K9cr (3 entities in total)
Functional Keywords	transcription, epigenetic, histone reader
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	35390.65
Authors	Vann, K.R.,Klein, B.J.,Kutateladze, T.G. (deposition date: 2018-09-19, release date: 2018-11-14, Last modification date: 2023-11-15)
Primary citation	Klein, B.J.,Vann, K.R.,Andrews, F.H.,Wang, W.W.,Zhang, J.,Zhang, Y.,Beloglazkina, A.A.,Mi, W.,Li, Y.,Li, H.,Shi, X.,Kutateladze, A.G.,Strahl, B.D.,Liu, W.R.,Kutateladze, T.G. Structural insights into the pi-pi-pi stacking mechanism and DNA-binding activity of the YEATS domain. Nat Commun, 9:4574-4574, 2018 Cited by PubMed: 30385749 DOI: 10.1038/s41467-018-07072-6 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.525 Å)

Structure validation