6MHF
Galphai3 co-crystallized with GIV/Girdin
Summary for 6MHF
| Entry DOI | 10.2210/pdb6mhf/pdb |
| Descriptor | Guanine nucleotide-binding protein G(k) subunit alpha, Girdin, GUANOSINE-5'-DIPHOSPHATE, ... (5 entities in total) |
| Functional Keywords | exchange, modulator, gpcr, inhibitory, signaling protein |
| Biological source | Rattus norvegicus (Rat) More |
| Total number of polymer chains | 2 |
| Total formula weight | 43914.37 |
| Authors | Rees, S.D.,Kalogriopoulos, N.A.,Ngo, T.,Kopcho, N.,Ilatovskiy, A.,Sun, N.,Komives, E.,Chang, G.,Ghosh, P.,Kufareva, I. (deposition date: 2018-09-17, release date: 2019-07-31, Last modification date: 2023-10-11) |
| Primary citation | Kalogriopoulos, N.A.,Rees, S.D.,Ngo, T.,Kopcho, N.J.,Ilatovskiy, A.V.,Sun, N.,Komives, E.A.,Chang, G.,Ghosh, P.,Kufareva, I. Structural basis for GPCR-independent activation of heterotrimeric Gi proteins. Proc.Natl.Acad.Sci.USA, 116:16394-16403, 2019 Cited by PubMed: 31363053DOI: 10.1073/pnas.1906658116 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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