6MAR

HIV-1 Envelope Glycoprotein Clone BG505 delCT N332T in complex with broadly neutralizing antibody Fab PGT151

Summary for 6MAR

• Entry DOI: 10.2210/pdb6mar/pdb
• EMDB information: 9062
• Descriptor: Immunoglobulin G PGT151 Fab, Heavy chain, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (13 entities in total)
• Functional Keywords: fusion protein-fab complex, membrane protein
• Biological source: Homo sapiens; More
• Total number of polymer chains: 10
• Total formula weight: 366670.05

Authors

Berndsen, Z.T.,Ward, A.B. (deposition date: 2018-08-28, release date: 2018-09-26, Last modification date: 2020-07-29)

• Primary citation: Cao, L.,Pauthner, M.,Andrabi, R.,Rantalainen, K.,Berndsen, Z.,Diedrich, J.K.,Menis, S.,Sok, D.,Bastidas, R.,Park, S.R.,Delahunty, C.M.,He, L.,Guenaga, J.,Wyatt, R.T.,Schief, W.R.,Ward, A.B.,Yates, J.R.,Burton, D.R.,Paulson, J.C.; Differential processing of HIV envelope glycans on the virus and soluble recombinant trimer.; Nat Commun, 9:3693-3693, 2018; PubMed: 30209313; DOI: 10.1038/s41467-018-06121-4

Experimental method

ELECTRON MICROSCOPY (4.5 Å)