6M82

Crystal structure of TylM1 Y14paF bound to SAH and dTDP-phenol

Summary for 6M82

DescriptordTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phenoxy)phosphoryl]oxy}phosphoryl]thymidine, ... (5 entities in total)
Functional Keywordstylm1, n-methyltransferase, transferase
Biological sourceStreptomyces fradiae
Total number of polymer chains1
Total molecular weight29461.66
Authors
Fick, R.J.,McDole, B.G.,Trievel, R.C. (deposition date: 2018-08-21, release date: 2019-03-13)
Primary citation
Fick, R.J.,Horowitz, S.,McDole, B.G.,Clay, M.C.,Mehl, R.A.,Al-Hashimi, H.M.,Scheiner, S.,Trievel, R.C.
Structural and Functional Characterization of Sulfonium Carbon-Oxygen Hydrogen Bonding in the Deoxyamino Sugar Methyltransferase TylM1.
Biochemistry, 2019
PubMed: 30810306 (PDB entries with the same primary citation)
DOI: 10.1021/acs.biochem.8b01141
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.3971 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.17230 0.6% 1.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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More Biological unit images

Molmil generated image of 6m82
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Molmil generated image of 6m82
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Molmil generated image of 6m82
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(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (6m82.pdb1.gz [164.33 KB])