6M81
Crystal structure of TylM1 Y14F bound to SAH and dTDP-phenol
Summary for 6M81
| Entry DOI | 10.2210/pdb6m81/pdb |
| Descriptor | dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phenoxy)phosphoryl]oxy}phosphoryl]thymidine, ... (4 entities in total) |
| Functional Keywords | tylm1, n-methyltransferase, transferase |
| Biological source | Streptomyces fradiae |
| Total number of polymer chains | 4 |
| Total formula weight | 117538.30 |
| Authors | Fick, R.J.,McDole, B.G.,Trievel, R.C. (deposition date: 2018-08-21, release date: 2019-03-13, Last modification date: 2024-03-13) |
| Primary citation | Fick, R.J.,Horowitz, S.,McDole, B.G.,Clay, M.C.,Mehl, R.A.,Al-Hashimi, H.M.,Scheiner, S.,Trievel, R.C. Structural and Functional Characterization of Sulfonium Carbon-Oxygen Hydrogen Bonding in the Deoxyamino Sugar Methyltransferase TylM1. Biochemistry, 58:2152-2159, 2019 Cited by PubMed: 30810306DOI: 10.1021/acs.biochem.8b01141 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.782 Å) |
Structure validation
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