6LXT

Structure of post fusion core of 2019-nCoV S2 subunit

Summary for 6LXT

Entry DOI	10.2210/pdb6lxt/pdb
Descriptor	Spike protein S2, Spike protein S2, TETRAETHYLENE GLYCOL, ZINC ION (3 entities in total)
Functional Keywords	2019-ncov, hr1 and hr2 domain, virus, viral protein
Biological source	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) More
Total number of polymer chains	6
Total formula weight	84658.01
Authors	Zhu, Y.,Sun, F. (deposition date: 2020-02-11, release date: 2020-02-26, Last modification date: 2023-11-29)
Primary citation	Xia, S.,Liu, M.,Wang, C.,Xu, W.,Lan, Q.,Feng, S.,Qi, F.,Bao, L.,Du, L.,Liu, S.,Qin, C.,Sun, F.,Shi, Z.,Zhu, Y.,Jiang, S.,Lu, L. Inhibition of SARS-CoV-2 (previously 2019-nCoV) infection by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to mediate membrane fusion. Cell Res., 30:343-355, 2020 Cited by PubMed: 32231345 DOI: 10.1038/s41422-020-0305-x PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation