6KXF

The ishigamide ketosynthase/chain length factor

Summary for 6KXF

Entry DOI	10.2210/pdb6kxf/pdb
Descriptor	Ketosynthase, ACP, [(3~{R})-2,2-dimethyl-4-[[3-[2-[[(~{E})-oct-2-enoyl]amino]ethylamino]-3-oxidanylidene-propyl]amino]-3-oxidanyl-4-oxidanylidene-butyl] dihydrogen phosphate, ... (5 entities in total)
Functional Keywords	polyketide synthase, transferase
Biological source	Streptomyces sp. MSC090213JE08 More
Total number of polymer chains	3
Total formula weight	90872.06
Authors	Du, D.,Katsuyama, Y.,Horiuchi, M.,Fushinobu, S.,Chen, A.,Davis, T.,Burkart, M.,Ohnishi, Y. (deposition date: 2019-09-10, release date: 2020-05-06, Last modification date: 2020-07-08)
Primary citation	Du, D.,Katsuyama, Y.,Horiuchi, M.,Fushinobu, S.,Chen, A.,Davis, T.D.,Burkart, M.D.,Ohnishi, Y. Structural basis for selectivity in a highly reducing type II polyketide synthase. Nat.Chem.Biol., 16:776-782, 2020 Cited by PubMed: 32367018 DOI: 10.1038/s41589-020-0530-0 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.98 Å)

Structure validation