6KUZ

E.coli beta-galactosidase (E537Q) in complex with fluorescent probe KSL01

Summary for 6KUZ

• Entry DOI: 10.2210/pdb6kuz/pdb
• Descriptor: Beta-galactosidase, 3-(1,3-benzothiazol-2-yl)-2-[[4-[(2~{S},3~{R},4~{S},5~{R},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxyphenyl]methoxy]-5-methyl-benzaldehyde, SODIUM ION, ... (7 entities in total)
• Functional Keywords: beta-galactosidase, fluorescent probe, hydrolase
• Biological source: Escherichia coli K-12
• Total number of polymer chains: 4
• Total formula weight: 471853.33

Authors

Chen, X.,Hu, Y.L.,Li, X.K.,Guo, Y.,Li, J. (deposition date: 2019-09-03, release date: 2020-07-08, Last modification date: 2023-11-22)

• Primary citation: Li, X.,Qiu, W.,Li, J.,Chen, X.,Hu, Y.,Gao, Y.,Shi, D.,Li, X.,Lin, H.,Hu, Z.,Dong, G.,Sheng, C.,Jiang, B.,Xia, C.,Kim, C.Y.,Guo, Y.,Li, J.; First-generation species-selective chemical probes for fluorescence imaging of human senescence-associated beta-galactosidase.; Chem Sci, 11:7292-7301, 2020; PubMed: 34123013; DOI: 10.1039/d0sc01234c

Experimental method

X-RAY DIFFRACTION (2.83 Å)