6JPB

Rabbit Cav1.1-Diltiazem Complex

Summary for 6JPB

EMDB information9869
DescriptorVoltage-dependent L-type calcium channel subunit alpha-1S, Voltage-dependent calcium channel gamma-1 subunit, Voltage-dependent L-type calcium channel subunit beta-1, ... (12 entities in total)
Functional Keywordsmembrane protein complex modulated by fda approved drug., membrane protein
Biological sourceOryctolagus cuniculus (Rabbit)
Total number of polymer chains5
Total molecular weight473331.3
Authors
Zhao, Y.,Huang, G.,Wu, J.,Yan, N. (deposition date: 2019-03-26, release date: 2019-06-12)
Primary citation
Zhao, Y.,Huang, G.,Wu, J.,Yan, N.
Molecular basis for the modulation of L-type voltage-gated Ca2+ channels by antagonistic and agonistic compounds
To Be Published,
Experimental method
ELECTRON MICROSCOPY
?

Structure validation

ClashscoreRamachandran outliersSidechain outliers21 0.4% 4.6%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures