6JMR

CD98hc extracellular domain bound to HBJ127 Fab and MEM-108 Fab

Summary for 6JMR

EMDB information9850
DescriptorAntibody, 4F2 cell-surface antigen heavy chain, N-ACETYL-D-GLUCOSAMINE, ... (6 entities in total)
Functional Keywordstransporter, glycoprotein, complex, membrane protein, membrane protein-immune system complex, membrane protein/immune system
Biological sourceMus musculus
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Total number of polymer chains5
Total molecular weight162927.18
Authors
Primary citation
Lee, Y.,Wiriyasermkul, P.,Jin, C.,Quan, L.,Ohgaki, R.,Okuda, S.,Kusakizako, T.,Nishizawa, T.,Oda, K.,Ishitani, R.,Yokoyama, T.,Nakane, T.,Shirouzu, M.,Endou, H.,Nagamori, S.,Kanai, Y.,Nureki, O.
Cryo-EM structure of the human L-type amino acid transporter 1 in complex with glycoprotein CD98hc.
Nat.Struct.Mol.Biol., 26:510-517, 2019
PubMed: 31160781 (PDB entries with the same primary citation)
DOI: 10.1038/s41594-019-0237-7
MImport into Mendeley
Experimental method
ELECTRON MICROSCOPY
?

Structure validation

ClashscoreRamachandran outliersSidechain outliers8 0.1% 0.4%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures