6JMQ

LAT1-CD98hc complex bound to MEM-108 Fab

Summary for 6JMQ

EMDB information9849
DescriptorLarge neutral amino acids transporter small subunit 1, 4F2 cell-surface antigen heavy chain, Antibody, ... (6 entities in total)
Functional Keywordstransporter, glycoprotein, complex, membrane protein, membrane protein-immune system complex, membrane protein/immune system
Biological sourceHomo sapiens (Human)
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Total number of polymer chains4
Total molecular weight172957.69
Authors
Lee, Y.,Nishizawa, T.,Kusakizako, T.,Oda, K.,Ishitani, R.,Nakane, T.,Nureki, O. (deposition date: 2019-03-13, release date: 2019-06-19)
Primary citation
Lee, Y.,Wiriyasermkul, P.,Jin, C.,Quan, L.,Ohgaki, R.,Okuda, S.,Kusakizako, T.,Nishizawa, T.,Oda, K.,Ishitani, R.,Yokoyama, T.,Nakane, T.,Shirouzu, M.,Endou, H.,Nagamori, S.,Kanai, Y.,Nureki, O.
Cryo-EM structure of the human L-type amino acid transporter 1 in complex with glycoprotein CD98hc.
Nat.Struct.Mol.Biol., 26:510-517, 2019
PubMed: 31160781 (PDB entries with the same primary citation)
DOI: 10.1038/s41594-019-0237-7
MImport into Mendeley
Experimental method
ELECTRON MICROSCOPY
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Structure validation

ClashscoreRamachandran outliersSidechain outliers4 0.1% 0.2%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures