6JCJ

Structure of crolibulin in complex with tubulin

Summary for 6JCJ

• Entry DOI: 10.2210/pdb6jcj/pdb
• Descriptor: Tubulin alpha-1B chain, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Tubulin beta-2B chain, ... (11 entities in total)
• Functional Keywords: cbsis, colchicine binding site inhibitors, cell cycle
• Biological source: Sus scrofa (Pig); More
• Total number of polymer chains: 6
• Total formula weight: 264810.51

Authors

Zhang, Z.,Yang, J. (deposition date: 2019-01-29, release date: 2019-03-13, Last modification date: 2023-11-22)

• Primary citation: Zhang, Z.,Wang, C.,Ma, L.,Jiang, X.,Wu, C.,Wang, Y.,Jiang, Y.,Zheng, W.,Yang, Y.,Ma, Y.,Yang, J.; Molecular mechanism of crolibulin in complex with tubulin provides a rationale for drug design.; Biochem. Biophys. Res. Commun., 511:381-386, 2019; PubMed: 30803758; DOI: 10.1016/j.bbrc.2019.02.064

Experimental method

X-RAY DIFFRACTION (2.5 Å)