6J67

Crystal structure of the compound 34 in a complex with TRF2

Summary for 6J67

• Entry DOI: 10.2210/pdb6j67/pdb
• Related PRD ID: PRD_002316
• Descriptor: Telomeric repeat-binding factor 2, 3FB-PHE-B8R-LEU-5XU-PRO (3 entities in total)
• Functional Keywords: telomere proteins, shelterin complex, trf2, apollo, inhibitor, dna binding protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 24587.74

Authors

Chen, Y.,Yang, Y.,Lei, M. (deposition date: 2019-01-14, release date: 2019-02-13, Last modification date: 2023-11-22)

• Primary citation: Chen, X.,Liu, L.,Chen, Y.,Yang, Y.,Yang, C.Y.,Guo, T.,Lei, M.,Sun, H.,Wang, S.; Cyclic Peptidic Mimetics of Apollo Peptides Targeting Telomeric Repeat Binding Factor 2 (TRF2) and Apollo Interaction.; ACS Med Chem Lett, 9:507-511, 2018; PubMed: 29795768; DOI: 10.1021/acsmedchemlett.8b00152

Experimental method

X-RAY DIFFRACTION (2.05 Å)