6IVZ

Crystal structure of 5A ScFv complexed with YFV-China sE in postfusion state

Summary for 6IVZ

Entry DOI	10.2210/pdb6ivz/pdb
Descriptor	Envelope protein, Heavy chain of monoclonal antibody 5A, Light chain of monoclonal antibody 5A, ... (4 entities in total)
Functional Keywords	yellow fever virus, neutralizing monoclonal antibody, envelope protein, flavivirus, viral protein, viral protein-immune system complex, viral protein/immune system
Biological source	Yellow fever virus More
Total number of polymer chains	3
Total formula weight	70016.35
Authors	Lu, X.S.,Xiao, H.X.,Li, S.H.,Pang, X.F. (deposition date: 2018-12-04, release date: 2019-02-13, Last modification date: 2019-02-27)
Primary citation	Lu, X.,Xiao, H.,Li, S.,Pang, X.,Song, J.,Liu, S.,Cheng, H.,Li, Y.,Wang, X.,Huang, C.,Guo, T.,Ter Meulen, J.,Daffis, S.,Yan, J.,Dai, L.,Rao, Z.,Klenk, H.D.,Qi, J.,Shi, Y.,Gao, G.F. Double Lock of a Human Neutralizing and Protective Monoclonal Antibody Targeting the Yellow Fever Virus Envelope. Cell Rep, 26:438-446.e5, 2019 Cited by PubMed: 30625326 DOI: 10.1016/j.celrep.2018.12.065 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation