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6IUV

Crystal structure of influenza A virus H5 hemagglutinin globular head in complex with the Fab of antibody 3C11

Summary for 6IUV
Entry DOI10.2210/pdb6iuv/pdb
DescriptorHemagglutinin, 3C11 Light Chain, 3C11 Heavy Chain, ... (5 entities in total)
Functional Keywordsinfluenza virus, hpai, h5n1, neutralizing antibody, epitope, major vulnerable site, vaccine development, immune system
Biological sourceInfluenza A virus (A/Hong Kong/482/97(H5N1)) (A/Hong Kong/482/97(H5N1))
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Total number of polymer chains6
Total formula weight149036.50
Authors
Wang, P.,Zuo, Y.,Sun, J.,Zhang, L.,Wang, X. (deposition date: 2018-11-30, release date: 2019-01-16, Last modification date: 2023-11-22)
Primary citationWang, P.,Zuo, Y.,Sun, J.,Zuo, T.,Zhang, S.,Guo, S.,Shi, X.,Liang, M.,Zhou, P.,Zhang, L.,Wang, X.
Structural and functional definition of a vulnerable site on the hemagglutinin of highly pathogenic avian influenza A virus H5N1.
J. Biol. Chem., 294:4290-4303, 2019
Cited by
PubMed: 30737282
DOI: 10.1074/jbc.RA118.007008
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.332 Å)
Structure validation

217705

數據於2024-03-27公開中

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