6IRA

Structure of the human GluN1/GluN2A NMDA receptor in the glutamate/glycine-bound state at pH 7.8

Summary for 6IRA

• Entry DOI: 10.2210/pdb6ira/pdb
• Related: 6IRF 6IRG 6IRH
• EMDB information: 9714 9715 9716 9717
• Descriptor: Glutamate receptor ionotropic, NMDA 2A, Glutamate receptor ionotropic, NMDA 1 (2 entities in total)
• Functional Keywords: ionotropic glutamate receptors, nmda receptors, synaptic protein, membrane protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 381880.19

Authors

Zhang, J.,Chang, S.,Zhang, X.,Zhu, S. (deposition date: 2018-11-12, release date: 2019-01-16, Last modification date: 2019-06-05)

• Primary citation: Zhang, J.B.,Chang, S.,Xu, P.,Miao, M.,Wu, H.,Zhang, Y.,Zhang, T.,Wang, H.,Zhang, J.,Xie, C.,Song, N.,Luo, C.,Zhang, X.,Zhu, S.; Structural Basis of the Proton Sensitivity of Human GluN1-GluN2A NMDA Receptors; Cell Rep, 25:3582-3590.e4, 2018; PubMed: 30590034; DOI: 10.1016/j.celrep.2018.11.071

Experimental method

ELECTRON MICROSCOPY (4.5 Å)