6IQG

X-ray crystal structure of Fc and peptide complex

Summary for 6IQG

Entry DOI	10.2210/pdb6iqg/pdb
Descriptor	Immunoglobulin gamma-1 heavy chain, 18-mer peptide G(HCS)DCAYHRGELVWCT(HCS)H(NH2), 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
Functional Keywords	fc, complex, immune system
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	54504.43
Authors	Adachi, M.,Ito, Y. (deposition date: 2018-11-08, release date: 2019-02-13, Last modification date: 2024-03-13)
Primary citation	Kishimoto, S.,Nakashimada, Y.,Yokota, R.,Hatanaka, T.,Adachi, M.,Ito, Y. Site-Specific Chemical Conjugation of Antibodies by Using Affinity Peptide for the Development of Therapeutic Antibody Format. Bioconjug. Chem., 30:698-702, 2019 Cited by PubMed: 30606013 DOI: 10.1021/acs.bioconjchem.8b00865 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.998 Å)

Structure validation