6IEN

Substrate/product bound Argininosuccinate lyase from Mycobacterium tuberculosis

Summary for 6IEN

Entry DOI	10.2210/pdb6ien/pdb
Descriptor	Argininosuccinate lyase, ARGININOSUCCINATE, FUMARIC ACID, ... (7 entities in total)
Functional Keywords	arginine biosynthesis, tetramer, aspartase/fumarase, concerted movement, lyase
Biological source	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Total number of polymer chains	4
Total formula weight	200891.18
Authors	Paul, A.,Mishra, A.,Surolia, A.,Vijayan, M. (deposition date: 2018-09-14, release date: 2019-02-20, Last modification date: 2023-11-15)
Primary citation	Paul, A.,Mishra, A.,Surolia, A.,Vijayan, M. Structural studies on M. tuberculosis argininosuccinate lyase and its liganded complex: Insights into catalytic mechanism. IUBMB Life, 71:643-652, 2019 Cited by PubMed: 30615268 DOI: 10.1002/iub.2000 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation