6IEK

Structure of RVFV Gn and human monoclonal antibody R12

Summary for 6IEK

DescriptorNSmGnGc, Heavy chain of Fab R12, Light chain of Fab R12, ... (4 entities in total)
Functional Keywordsrvfv, antibody, structural protein, structural protein-immune system complex, structural protein/immune system
Biological sourceRift valley fever virus (RVFV)
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Total number of polymer chains6
Total molecular weight165610.16
Authors
Wang, Q.H.,Wu, Y.,Gao, F.,Qi, J.X.,Gao, G.F. (deposition date: 2018-09-14, release date: 2019-04-10)
Primary citation
Wang, Q.,Ma, T.,Wu, Y.,Chen, Z.,Zeng, H.,Tong, Z.,Gao, F.,Qi, J.,Zhao, Z.,Chai, Y.,Yang, H.,Wong, G.,Bi, Y.,Wu, L.,Shi, R.,Yang, M.,Song, J.,Jiang, H.,An, Z.,Wang, J.,Yilma, T.D.,Shi, Y.,Liu, W.J.,Liang, M.,Qin, C.,Gao, G.F.,Yan, J.
Neutralization mechanism of human monoclonal antibodies against Rift Valley fever virus.
Nat Microbiol, 2019
PubMed: 30936489 (PDB entries with the same primary citation)
DOI: 10.1038/s41564-019-0411-z
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.7 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.25970 1.3% 6.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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More Biological unit images

Molmil generated image of 6iek
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Molmil generated image of 6iek
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Molmil generated image of 6iek
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(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (6iek.pdb2.gz [240.72 KB])
Coordinate files for Biological unit (6iek.pdb1.gz [239.52 KB])