6IEK

Structure of RVFV Gn and human monoclonal antibody R12

Summary for 6IEK

• Entry DOI: 10.2210/pdb6iek/pdb
• Descriptor: NSmGnGc, Heavy chain of Fab R12, Light chain of Fab R12, ... (4 entities in total)
• Functional Keywords: rvfv, antibody, structural protein, structural protein-immune system complex, structural protein/immune system
• Biological source: Rift valley fever virus (RVFV); More
• Total number of polymer chains: 6
• Total formula weight: 165610.16

Authors

Wang, Q.H.,Wu, Y.,Gao, F.,Qi, J.X.,Gao, G.F. (deposition date: 2018-09-14, release date: 2019-04-10, Last modification date: 2019-07-10)

• Primary citation: Wang, Q.,Ma, T.,Wu, Y.,Chen, Z.,Zeng, H.,Tong, Z.,Gao, F.,Qi, J.,Zhao, Z.,Chai, Y.,Yang, H.,Wong, G.,Bi, Y.,Wu, L.,Shi, R.,Yang, M.,Song, J.,Jiang, H.,An, Z.,Wang, J.,Yilma, T.D.,Shi, Y.,Liu, W.J.,Liang, M.,Qin, C.,Gao, G.F.,Yan, J.; Neutralization mechanism of human monoclonal antibodies against Rift Valley fever virus.; Nat Microbiol, 4:1231-1241, 2019; PubMed: 30936489; DOI: 10.1038/s41564-019-0411-z

Experimental method

X-RAY DIFFRACTION (2.7 Å)