6IBD

The Phosphatase and C2 domains of Human SHIP1

Summary for 6IBD

Entry DOI	10.2210/pdb6ibd/pdb
Descriptor	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 (2 entities in total)
Functional Keywords	phosphatidylinositol phosphate phosphatase, alzheimer's disease, hydrolase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	52877.57
Authors	Bradshaw, W.J.,Williams, E.P.,Fernandez-Cid, A.,Burgess-Brown, N.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.,Bountra, C.,Gileadi, O. (deposition date: 2018-11-29, release date: 2019-01-16, Last modification date: 2024-02-14)
Primary citation	Bradshaw, W.J.,Kennedy, E.C.,Moreira, T.,Smith, L.A.,Chalk, R.,Katis, V.L.,Benesch, J.L.P.,Brennan, P.E.,Murphy, E.J.,Gileadi, O. Regulation of inositol 5-phosphatase activity by the C2 domain of SHIP1 and SHIP2. Structure, 2024 Cited by PubMed: 38309262 DOI: 10.1016/j.str.2024.01.005 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.48 Å)

Structure validation