6I4N
Dodecamer DNA containing the synthetic base pair P-Z in complex with a pyrrole-imidazole polyamide
6I4N の概要
エントリーDOI | 10.2210/pdb6i4n/pdb |
分子名称 | DNA (5'-D(*CP*GP*AP*TP*(DP)P*TP*AP*(DZ)P*AP*TP*CP*G)-3'), 3-[3-[[4-[[4-[[4-[[4-[[(2~{R})-2-azaniumyl-4-[[1-methyl-4-[[1-methyl-4-[[1-methyl-4-[(1-methylimidazol-2-yl)carbonylamino]pyrrol-2-yl]carbonylamino]pyrrol-2-yl]carbonylamino]pyrrol-2-yl]carbonylamino]butanoyl]amino]-1-methyl-imidazol-2-yl]carbonylamino]-1-methyl-pyrrol-2-yl]carbonylamino]-1-methyl-pyrrol-2-yl]carbonylamino]-1-methyl-pyrrol-2-yl]carbonylamino]propanoylamino]propyl-dimethyl-azanium (2 entities in total) |
機能のキーワード | dna, synthetic base pair, z, p, pyrrole-imidazole polyamide |
由来する生物種 | synthetic construct |
タンパク質・核酸の鎖数 | 2 |
化学式量合計 | 8652.18 |
構造登録者 | |
主引用文献 | Padroni, G.,Withers, J.M.,Taladriz-Sender, A.,Reichenbach, L.F.,Parkinson, J.A.,Burley, G.A. Sequence-Selective Minor Groove Recognition of a DNA Duplex Containing Synthetic Genetic Components. J.Am.Chem.Soc., 141:9555-9563, 2019 Cited by PubMed: 31117639DOI: 10.1021/jacs.8b12444 主引用文献が同じPDBエントリー |
実験手法 | SOLUTION NMR |
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