6I3M

eIF2B:eIF2 complex, phosphorylated on eIF2 alpha serine 52.

Summary for 6I3M

• Entry DOI: 10.2210/pdb6i3m/pdb
• EMDB information: 4404
• Descriptor: Translation initiation factor eIF-2B subunit alpha, Translation initiation factor eIF-2B subunit delta, Translation initiation factor eIF-2B subunit beta, ... (8 entities in total)
• Functional Keywords: translational control eif2 phosphorylation integrated stress response eif2b translation, translation
• Biological source: Saccharomyces cerevisiae S288C (Baker's yeast); More
• Total number of polymer chains: 16
• Total formula weight: 838127.37

Authors

Adomavicius, T.,Roseman, A.M.,Pavitt, G.D. (deposition date: 2018-11-06, release date: 2019-05-22, Last modification date: 2019-11-06)

• Primary citation: Adomavicius, T.,Guaita, M.,Zhou, Y.,Jennings, M.D.,Latif, Z.,Roseman, A.M.,Pavitt, G.D.; The structural basis of translational control by eIF2 phosphorylation.; Nat Commun, 10:2136-2136, 2019; PubMed: 31086188; DOI: 10.1038/s41467-019-10167-3

Experimental method

ELECTRON MICROSCOPY (3.93 Å)