6I30
Crystal structure of the AmpC from Pseudomonas aeruginosa with 1C
Summary for 6I30
Entry DOI | 10.2210/pdb6i30/pdb |
Descriptor | Class C beta-lactamase PDC-301, (3R)-3-(cyclohexylcarbonylamino)-2-oxidanyl-3,4-dihydro-1,2-benzoxaborinine-8-carboxylic acid (3 entities in total) |
Functional Keywords | cyclic boronates, antimicrobial resistance, beta-lactamase, antibiotic, hydrolase |
Biological source | Pseudomonas aeruginosa |
Total number of polymer chains | 1 |
Total formula weight | 39616.49 |
Authors | Brem, J.,Cahill, S.T.,McDonough, M.A.,Schofield, C.J. (deposition date: 2018-11-02, release date: 2019-02-20, Last modification date: 2024-01-24) |
Primary citation | Cahill, S.T.,Tyrrell, J.M.,Navratilova, I.H.,Calvopina, K.,Robinson, S.W.,Lohans, C.T.,McDonough, M.A.,Cain, R.,Fishwick, C.W.G.,Avison, M.B.,Walsh, T.R.,Schofield, C.J.,Brem, J. Studies on the inhibition of AmpC and other beta-lactamases by cyclic boronates. Biochim Biophys Acta Gen Subj, 1863:742-748, 2019 Cited by PubMed: 30738906DOI: 10.1016/j.bbagen.2019.02.004 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.21 Å) |
Structure validation
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