6I2Y

Human STK10 bound to Foretinib

Summary for 6I2Y

• Entry DOI: 10.2210/pdb6i2y/pdb
• Descriptor: Serine/threonine-protein kinase 10, N-(3-fluoro-4-{[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinolin-4-yl]oxy}phenyl)-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide (2 entities in total)
• Functional Keywords: kinase, inhibitor, complex, lok, transferase, foretinib
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 69746.32

Authors

Sorrell, F.J.,Berger, B.-T.,Oerum, S.,von Delft, F.,Bountra, C.,Arrowsmith, C.,Edwards, A.M.,Knapp, S.,Elkins, J.M. (deposition date: 2018-11-02, release date: 2018-12-12)

• Primary citation: Sorrell, F.J.,Elkins, J.M.; Human STK10 bound to GW683134; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.56 Å)