6I0X

Porphyromonas gingivalis peptidylarginine deminase (PPAD) mutant G231N/E232T/N235D in complex with Cl-amidine.

Summary for 6I0X

Entry DOI	10.2210/pdb6i0x/pdb
Descriptor	Peptidylarginine deiminase, SODIUM ION, N-[(1S)-1-(AMINOCARBONYL)-4-(ETHANIMIDOYLAMINO)BUTYL]BENZAMIDE, ... (5 entities in total)
Functional Keywords	citrullination, odontopathogenic virulence factor, arginine demininase, periodontal disease, rheumatoid arthitis, hydrolase
Biological source	Porphyromonas gingivalis (strain ATCC BAA-308 / W83)
Total number of polymer chains	2
Total formula weight	99273.44
Authors	Gomis-Ruth, F.X.,Goulas, T.,Sola, M.,Potempa, J. (deposition date: 2018-10-26, release date: 2019-01-23, Last modification date: 2024-01-24)
Primary citation	Bereta, G.,Goulas, T.,Madej, M.,Bielecka, E.,Sola, M.,Potempa, J.,Xavier Gomis-Ruth, F. Structure, function, and inhibition of a genomic/clinical variant of Porphyromonas gingivalis peptidylarginine deiminase. Protein Sci., 28:478-486, 2019 Cited by PubMed: 30638292 DOI: 10.1002/pro.3571 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation