6HZY

Crystal structure of a bacterial fucosidase with inhibitor FucPUG

Summary for 6HZY

Entry DOI	10.2210/pdb6hzy/pdb
Descriptor	Alpha-L-fucosidase, 1,2-ETHANEDIOL, [(~{Z})-[(3~{S},4~{R},5~{S},6~{S})-6-methyl-3,4,5-tris(oxidanyl)oxan-2-ylidene]amino] ~{N}-phenylcarbamate, ... (5 entities in total)
Functional Keywords	hydrolase
Biological source	Bacteroides thetaiotaomicron VPI-5482
Total number of polymer chains	2
Total formula weight	111980.14
Authors	Wu, L.,Davies, G.J.,Stubbs, K.A.,Coyle, T.,Debowski, A.W. (deposition date: 2018-10-24, release date: 2019-02-20, Last modification date: 2024-01-24)
Primary citation	Coyle, T.,Wu, L.,Debowski, A.W.,Davies, G.J.,Stubbs, K.A. Synthetic and Crystallographic Insight into Exploiting sp2Hybridization in the Development of alpha-l-Fucosidase Inhibitors. Chembiochem, 20:1365-1368, 2019 Cited by PubMed: 30663832 DOI: 10.1002/cbic.201800710 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation