6HUY

HmdII from Desulfurobacterium thermolithotrophum reconstitued with Fe-guanylylpyridinol (FeGP) cofactor and co-crystallized with methenyl-tetrahydrofolate form A

Summary for 6HUY

Entry DOI	10.2210/pdb6huy/pdb
Descriptor	Coenzyme F420-dependent N(5),N(10)-methenyltetrahydromethanopterin reductase-related protein, iron-guanylyl pyridinol cofactor, GLYCEROL, ... (8 entities in total)
Functional Keywords	hydrogenase, h2-activation, lateral gene-transfer, cofactor biosynthesis, tetrahydromethanopterin, tetrahydrofolate, paralog, sulfur-reducing bacteria, metalloenzyme, oxidoreductase
Biological source	Desulfurobacterium thermolithotrophum DSM 11699 More
Total number of polymer chains	4
Total formula weight	168287.98
Authors	Watanabe, T.,Wagner, T.,Huang, G.,Kahnt, J.,Ataka, K.,Ermler, U.,Shima, S. (deposition date: 2018-10-09, release date: 2019-01-09, Last modification date: 2024-01-24)
Primary citation	Watanabe, T.,Wagner, T.,Huang, G.,Kahnt, J.,Ataka, K.,Ermler, U.,Shima, S. The Bacterial [Fe]-Hydrogenase Paralog HmdII Uses Tetrahydrofolate Derivatives as Substrates. Angew. Chem. Int. Ed. Engl., 58:3506-3510, 2019 Cited by PubMed: 30600878 DOI: 10.1002/anie.201813465 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.25 Å)

Structure validation