Structure of the TRPML2 ELD at pH 6.5

Summary for 6HRR

DescriptorMucolipin-2, POTASSIUM ION, CHLORIDE ION, ... (6 entities in total)
Functional Keywordstrpml channel mucolipin cation channel endolysosomal system, membrane protein
Biological sourceHomo sapiens (Human)
Total number of polymer chains2
Total molecular weight46169.87
Bader, N.,Viet, K.K.,Wagner, A.,Hellmich, U.A. (deposition date: 2018-09-28, release date: 2019-06-19, Last modification date: 2019-08-14)
Primary citation
Viet, K.K.,Wagner, A.,Schwickert, K.,Hellwig, N.,Brennich, M.,Bader, N.,Schirmeister, T.,Morgner, N.,Schindelin, H.,Hellmich, U.A.
Structure of the Human TRPML2 Ion Channel Extracytosolic/Lumenal Domain.
Structure, 27:1246-1257.e5, 2019
PubMed: 31178222 (PDB entries with the same primary citation)
DOI: 10.1016/j.str.2019.04.016
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.1881 0.3% 2.5% 15.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution