Cholera toxin classical B-pentamer in complex with fucose

Summary for 6HMW

Related6HJD 5ELB
DescriptorCholera enterotoxin B-subunit, CALCIUM ION, BICINE, ... (5 entities in total)
Functional Keywordstoxin, cholera toxin, lectin, complex, fucose, protein-carbohydrate interactions, x-ray crystal structure
Biological sourceVibrio cholerae
Total number of polymer chains10
Total molecular weight120891.67
Krengel, U.,Heim, J.B. (deposition date: 2018-09-13, release date: 2019-08-14)
Primary citation
Heim, J.B.,Hodnik, V.,Heggelund, J.E.,Anderluh, G.,Krengel, U.
Crystal structures reveal that Lewis-x and fucose bind to secondary cholera toxin binding site
To Be Published,
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2495 0.1% 4.0% 1.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution