6HIP

Structure of SPF45 UHM bound to HIV-1 Rev ULM

Summary for 6HIP

Entry DOI	10.2210/pdb6hip/pdb
Descriptor	Splicing factor 45, HIV-1 Rev (41-49), TRYPTOPHAN, ... (5 entities in total)
Functional Keywords	splicing factor, viral protein, splicing
Biological source	Homo sapiens (Human) More
Total number of polymer chains	3
Total formula weight	24898.71
Authors	Pabis, M.,Corsini, L.,Sattler, M. (deposition date: 2018-08-30, release date: 2019-03-27, Last modification date: 2024-01-17)
Primary citation	Pabis, M.,Corsini, L.,Vincendeau, M.,Tripsianes, K.,Gibson, T.J.,Brack-Werner, R.,Sattler, M. Modulation of HIV-1 gene expression by binding of a ULM motif in the Rev protein to UHM-containing splicing factors. Nucleic Acids Res., 47:4859-4871, 2019 Cited by PubMed: 30892606 DOI: 10.1093/nar/gkz185 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.2 Å)

Structure validation