6HHQ
Crystal structure of compound C45 bound to the yeast 80S ribosome
This is a non-PDB format compatible entry.
Summary for 6HHQ
Entry DOI | 10.2210/pdb6hhq/pdb |
Descriptor | 25S ribosomal RNA, 60S ribosomal protein L8-A, 60S ribosomal protein L9-A, ... (86 entities in total) |
Functional Keywords | 80s ribosome, inhibitor, anti-cancer, ribosome |
Biological source | Saccharomyces cerevisiae More |
Total number of polymer chains | 159 |
Total formula weight | 6646164.98 |
Authors | Pellegrino, S.,Vanderwal, C.D.,Yusupov, M. (deposition date: 2018-08-28, release date: 2019-02-20, Last modification date: 2019-04-17) |
Primary citation | Pellegrino, S.,Meyer, M.,Konst, Z.A.,Holm, M.,Voora, V.K.,Kashinskaya, D.,Zanette, C.,Mobley, D.L.,Yusupova, G.,Vanderwal, C.D.,Blanchard, S.C.,Yusupov, M. Understanding the role of intermolecular interactions between lissoclimides and the eukaryotic ribosome. Nucleic Acids Res., 47:3223-3232, 2019 Cited by PubMed: 30759226DOI: 10.1093/nar/gkz053 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.10000049683 Å) |
Structure validation
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