6HD1
human STEAP4 bound to NADPH, FAD and heme.
Summary for 6HD1
| Entry DOI | 10.2210/pdb6hd1/pdb |
| Related | 6HCY |
| EMDB information | 0199 0200 |
| Descriptor | Metalloreductase STEAP4, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PROTOPORPHYRIN IX CONTAINING FE, ... (6 entities in total) |
| Functional Keywords | enzyme, metalloreductase, electron transfer, cofactor-binding, membrane protein |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 3 |
| Total formula weight | 164313.03 |
| Authors | Oosterheert, W.,van Bezouwen, L.S.,Rodenburg, R.N.P.,Forster, F.,Mattevi, A.,Gros, P. (deposition date: 2018-08-17, release date: 2018-10-24, Last modification date: 2020-07-29) |
| Primary citation | Oosterheert, W.,van Bezouwen, L.S.,Rodenburg, R.N.P.,Granneman, J.,Forster, F.,Mattevi, A.,Gros, P. Cryo-EM structures of human STEAP4 reveal mechanism of iron(III) reduction. Nat Commun, 9:4337-4337, 2018 Cited by PubMed: 30337524DOI: 10.1038/s41467-018-06817-7 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.8 Å) |
Structure validation
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