6H6K

The structure of the FKR mutant of the archaeal translation initiation factor 2 gamma subunit in complex with GDPCP, obtained in the absence of magnesium salts in the crystallization solution.

6H6K の概要

• エントリーDOI: 10.2210/pdb6h6k/pdb
• 分子名称: Translation initiation factor 2 subunit gamma, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, SODIUM ION, ... (5 entities in total)
• 機能のキーワード: translation initiation, aif2, aif2gamma, aif2gamma switches, g-protein, gtp-binding domain, translation gtpases, gtp hydrolysis, conformational changes, magnesium ions, translation
• 由来する生物種: Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 231136.84

構造登録者

Nikonov, O.,Kravchenko, O.,Nevskaya, N.,Stolboushkina, E.,Gabdulkhakov, A.,Garber, M.,Nikonov, S. (登録日: 2018-07-27, 公開日: 2019-04-17, 最終更新日: 2024-01-17)

• 主引用文献: Nikonov, O.,Kravchenko, O.,Nevskaya, N.,Stolboushkina, E.,Garber, M.,Nikonov, S.; The third structural switch in the archaeal translation initiation factor 2 (aIF2) molecule and its possible role in the initiation of GTP hydrolysis and the removal of aIF2 from the ribosome.; Acta Crystallogr D Struct Biol, 75:392-399, 2019; PubMed: 30988256; DOI: 10.1107/S2059798319002304

実験手法

X-RAY DIFFRACTION (2 Å)