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6H6K

The structure of the FKR mutant of the archaeal translation initiation factor 2 gamma subunit in complex with GDPCP, obtained in the absence of magnesium salts in the crystallization solution.

Summary for 6H6K
Entry DOI10.2210/pdb6h6k/pdb
DescriptorTranslation initiation factor 2 subunit gamma, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, SODIUM ION, ... (5 entities in total)
Functional Keywordstranslation initiation, aif2, aif2gamma, aif2gamma switches, g-protein, gtp-binding domain, translation gtpases, gtp hydrolysis, conformational changes, magnesium ions, translation
Biological sourceSulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
Total number of polymer chains5
Total formula weight231136.84
Authors
Nikonov, O.,Kravchenko, O.,Nevskaya, N.,Stolboushkina, E.,Gabdulkhakov, A.,Garber, M.,Nikonov, S. (deposition date: 2018-07-27, release date: 2019-04-17, Last modification date: 2024-01-17)
Primary citationNikonov, O.,Kravchenko, O.,Nevskaya, N.,Stolboushkina, E.,Garber, M.,Nikonov, S.
The third structural switch in the archaeal translation initiation factor 2 (aIF2) molecule and its possible role in the initiation of GTP hydrolysis and the removal of aIF2 from the ribosome.
Acta Crystallogr D Struct Biol, 75:392-399, 2019
Cited by
PubMed: 30988256
DOI: 10.1107/S2059798319002304
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation

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