6GY2

Crystal structure of human Plk1-PBD in complex with WSSSLATPPTLSSpTVLI phosphopeptide from BRCA2

Summary for 6GY2

Entry DOI	10.2210/pdb6gy2/pdb
Descriptor	Serine/threonine-protein kinase PLK1, Phosphopeptide of BRCA2, GLYCEROL, ... (4 entities in total)
Functional Keywords	phosphorylation, chromosomes alignement, dna repair, cell cycle
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	60158.24
Authors	Miron, S.,Ropars, V.,Zinn-Justin, S. (deposition date: 2018-06-28, release date: 2019-07-10, Last modification date: 2024-01-17)
Primary citation	Ehlen, A.,Martin, C.,Miron, S.,Julien, M.,Theillet, F.X.,Ropars, V.,Sessa, G.,Beaurepere, R.,Boucherit, V.,Duchambon, P.,El Marjou, A.,Zinn-Justin, S.,Carreira, A. Proper chromosome alignment depends on BRCA2 phosphorylation by PLK1. Nat Commun, 11:1819-1819, 2020 Cited by PubMed: 32286328 DOI: 10.1038/s41467-020-15689-9 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.11 Å)

Structure validation