Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

6GS6

Cyclophilin A single mutant D66A in complex with an inhibitor.

Summary for 6GS6
Entry DOI10.2210/pdb6gs6/pdb
DescriptorPeptidyl-prolyl cis-trans isomerase A, ethyl N-[(4-aminobenzyl)carbamoyl]glycinate, DIMETHYL SULFOXIDE, ... (4 entities in total)
Functional Keywordscyclophilins, cypa, cypa mutant, inhibitor, ppiase, complex, isomerase
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total formula weight18321.91
Authors
Georgiou, C.,De Simone, A.,Juarez-Jimenez, J.,Walkinshaw, M.D.,Michel, J. (deposition date: 2018-06-13, release date: 2019-06-26, Last modification date: 2024-01-17)
Primary citationJuarez-Jimenez, J.,Gupta, A.A.,Karunanithy, G.,May, A.,Georgiou, C.,Ioannidis, H.,De Simone, A.,Barlow, P.N.,Hulme, A.N.,Walkinshaw, M.D.,Baldwin, A.,Michel, J.
Dynamic design: manipulation of millisecond timescale motions on the energy landscape of cyclophilin A
Chem Sci, 2020
Cited by
DOI: 10.1039/C9SC04696H
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.16 Å)
Structure validation

217157

PDB entries from 2024-03-13

PDB statisticsPDBj update infoContact PDBjnumon