6GNM
Crystal Structure Of Sea Bream Transthyretin in complex with 2,2',4,4'-tetrahydroxybenzophenone (BP2)
Summary for 6GNM
Entry DOI | 10.2210/pdb6gnm/pdb |
Descriptor | Transthyretin, bis(2,4-dihydroxyphenyl)methanone (3 entities in total) |
Functional Keywords | transport protein, thyroxine disrupting chemicals, tdcs, 2, 2', 4, 4'-tetrahydroxybenzophenone, bp2 |
Biological source | Sparus aurata (Gilthead sea bream) |
Total number of polymer chains | 4 |
Total formula weight | 58312.81 |
Authors | Grundstrom, C.,Zhang, J.,Olofsson, A.,Andersson, P.L.,Sauer-Eriksson, A.E. (deposition date: 2018-05-31, release date: 2018-07-11, Last modification date: 2024-01-17) |
Primary citation | Zhang, J.,Grundstrom, C.,Brannstrom, K.,Iakovleva, I.,Lindberg, M.,Olofsson, A.,Andersson, P.L.,Sauer-Eriksson, A.E. Interspecies Variation between Fish and Human Transthyretins in Their Binding of Thyroid-Disrupting Chemicals. Environ. Sci. Technol., 52:11865-11874, 2018 Cited by PubMed: 30226982DOI: 10.1021/acs.est.8b03581 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.24 Å) |
Structure validation
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