6GNK

Exoenzyme S from Pseudomonas aeruginosa in complex with human 14-3-3 protein beta, trimeric crystal form bound to Carba-NAD

Summary for 6GNK

Entry DOI	10.2210/pdb6gnk/pdb
Related	3GN0 3GN8 3GNJ
Descriptor	14-3-3 protein beta/alpha, Exoenzyme S, CARBA-NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... (5 entities in total)
Functional Keywords	exos, pseudomonas aeruginosa, adp-ribosylation, nad, toxin
Biological source	Homo sapiens (Human) More
Total number of polymer chains	3
Total formula weight	83152.69
Authors	Karlberg, T.,Pinto, A.F.,Hornyak, P.,Thorsell, A.G.,Nareoja, K.,Schuler, H. (deposition date: 2018-05-31, release date: 2018-09-26, Last modification date: 2024-01-17)
Primary citation	Karlberg, T.,Hornyak, P.,Pinto, A.F.,Milanova, S.,Ebrahimi, M.,Lindberg, M.,Pullen, N.,Nordstrom, A.,Loverli, E.,Caraballo, R.,Wong, E.V.,Nareoja, K.,Thorsell, A.G.,Elofsson, M.,De La Cruz, E.M.,Bjorkegren, C.,Schuler, H. 14-3-3 proteins activate Pseudomonas exotoxins-S and -T by chaperoning a hydrophobic surface. Nat Commun, 9:3785-3785, 2018 Cited by PubMed: 30224724 DOI: 10.1038/s41467-018-06194-1 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.55 Å)

Structure validation