6GLL

Crystal structure of hMTH1 N33A in complex with LW14 in the presence of acetate

Summary for 6GLL

Descriptor7,8-dihydro-8-oxoguanine triphosphatase, 1~{H}-imidazo[4,5-b]pyridin-2-amine, SULFATE ION, ... (5 entities in total)
Functional Keywordsinhibitor, complex, hydrolase, dna repair, fragment
Biological sourceHomo sapiens (Human)
Total number of polymer chains2
Total molecular weight42894.42
Authors
Eberle, S.A.,Wiedmer, L.,Sledz, P.,Caflisch, A. (deposition date: 2018-05-23, release date: 2019-02-20)
Primary citation
Eberle, S.A.,Wiedmer, L.,Sledz, P.,Caflisch, A.
hMTH1 N33A in complex with LW14
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.395 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.1995 0.6% 1.6% 2.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 6gll
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Molmil generated image of 6gll
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Molmil generated image of 6gll
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More Biological unit images

Molmil generated image of 6gll
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Molmil generated image of 6gll
rotated about x axis by 90°
Molmil generated image of 6gll
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (6gll.pdb1.gz [31.73 KB])
Coordinate files for Biological unit (6gll.pdb2.gz [31.96 KB])