6GLC

Structure of phospho-Parkin bound to phospho-ubiquitin

Summary for 6GLC

• Entry DOI: 10.2210/pdb6glc/pdb
• Descriptor: E3 ubiquitin-protein ligase parkin, Polyubiquitin-B, ZINC ION, ... (7 entities in total)
• Functional Keywords: ubiquitin, parkin, phospho-ubiquitin, parkinson's disease, e3 ligase, rbr domain, mitophagy, ligase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 52532.38

Authors

Gladkova, C.,Maslen, S.L.,Skehel, J.M.,Komander, D. (deposition date: 2018-05-23, release date: 2018-06-13, Last modification date: 2024-01-17)

• Primary citation: Gladkova, C.,Maslen, S.L.,Skehel, J.M.,Komander, D.; Mechanism of parkin activation by PINK1.; Nature, 559:410-414, 2018; PubMed: 29995846; DOI: 10.1038/s41586-018-0224-x

Experimental method

X-RAY DIFFRACTION (1.8 Å)