6GLC

Structure of phospho-Parkin bound to phospho-ubiquitin

Summary for 6GLC

DescriptorE3 ubiquitin-protein ligase parkin, Polyubiquitin-B, ZINC ION, ... (7 entities in total)
Functional Keywordsubiquitin, parkin, phospho-ubiquitin, parkinson's disease, e3 ligase, rbr domain, mitophagy, ligase
Biological sourceHomo sapiens (Human)
Total number of polymer chains2
Total molecular weight52532.38
Authors
Gladkova, C.,Maslen, S.L.,Skehel, J.M.,Komander, D. (deposition date: 2018-05-23, release date: 2018-06-13, Last modification date: 2018-08-01)
Primary citation
Gladkova, C.,Maslen, S.L.,Skehel, J.M.,Komander, D.
Mechanism of parkin activation by PINK1.
Nature, 559:410-414, 2018
PubMed: 29995846 (PDB entries with the same primary citation)
DOI: 10.1038/s41586-018-0224-x
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.8 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.205300.9%2.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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Molmil generated image of 6glc
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