6GFM

Crystal structure of the Escherichia coli nucleosidase PpnN (pppGpp-form)

Summary for 6GFM

• Entry DOI: 10.2210/pdb6gfm/pdb
• Related: 6GFL
• Descriptor: Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase, guanosine 5'-(tetrahydrogen triphosphate) 3'-(trihydrogen diphosphate) (3 entities in total)
• Functional Keywords: ygdh, ppnn, allosteric enzyme, nucleotide metabolism, stringent response, antibiotic tolerance, persistence, fluoroquinolone, hydrolase
• Biological source: Escherichia coli K-12
• Total number of polymer chains: 1
• Total formula weight: 53927.31

Authors

Zhang, Y.,Baerentsen, R.L.,Gerdes, K.,Brodersen, D.E. (deposition date: 2018-05-01, release date: 2019-04-24, Last modification date: 2024-01-17)

• Primary citation: Zhang, Y.E.,Baerentsen, R.L.,Fuhrer, T.,Sauer, U.,Gerdes, K.,Brodersen, D.E.; (p)ppGpp Regulates a Bacterial Nucleosidase by an Allosteric Two-Domain Switch.; Mol.Cell, 74:1239-, 2019; PubMed: 31023582; DOI: 10.1016/j.molcel.2019.03.035

Experimental method

X-RAY DIFFRACTION (2.77 Å)