6GF6

Molecular basis of egg coat filament cross-linking: high-resolution structure of the partially deglycosylated ZP1 ZP-N1 domain homodimer

Summary for 6GF6

Entry DOI	10.2210/pdb6gf6/pdb
Related	6GF7 6GF8
Descriptor	Zona pellucida sperm-binding protein 1,Zona pellucida sperm-binding protein 1, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... (4 entities in total)
Functional Keywords	zona pellucida, zp1, zp-n domain, zp module, zp domain, egg coat filament cross-linking, egg coat penetration by sperm, cell adhesion
Biological source	Gallus gallus (Chicken) More
Total number of polymer chains	2
Total formula weight	31505.48
Authors	Nishimura, K.,Jovine, L. (deposition date: 2018-04-29, release date: 2019-06-19, Last modification date: 2020-07-29)
Primary citation	Nishimura, K.,Dioguardi, E.,Nishio, S.,Villa, A.,Han, L.,Matsuda, T.,Jovine, L. Molecular basis of egg coat cross-linking sheds light on ZP1-associated female infertility. Nat Commun, 10:3086-3086, 2019 Cited by PubMed: 31300655 DOI: 10.1038/s41467-019-10931-5 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation