6GCU

MET receptor in complex with InlB internalin domain and DARPin A3A

6GCU の概要

• エントリーDOI: 10.2210/pdb6gcu/pdb
• 分子名称: Hepatocyte growth factor receptor, Internalin B, DARPin A3A (3 entities in total)
• 機能のキーワード: receptor tyrosine kinase, bacterial invasion protein, artificial binding protein, signaling protein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 265413.05

構造登録者

Meyer, T.,Andres, F.,Iamele, L.,Gherardi, E.,Pluckthun, A.,Niemann, H.H. (登録日: 2018-04-19, 公開日: 2019-05-15, 最終更新日: 2024-01-17)

• 主引用文献: Andres, F.,Iamele, L.,Meyer, T.,Stuber, J.C.,Kast, F.,Gherardi, E.,Niemann, H.H.,Pluckthun, A.; Inhibition of the MET Kinase Activity and Cell Growth in MET-Addicted Cancer Cells by Bi-Paratopic Linking.; J.Mol.Biol., 431:2020-2039, 2019; PubMed: 30930049; DOI: 10.1016/j.jmb.2019.03.024

実験手法

X-RAY DIFFRACTION (6.001 Å)