6GCF

DNA binding domain of restriction endonuclease McrBC in complex with N4-methylcytosine DNA

Summary for 6GCF

• Entry DOI: 10.2210/pdb6gcf/pdb
• Related: 6GCD 6GCE
• Descriptor: 5-methylcytosine-specific restriction enzyme B, DNA (5'-D(*GP*AP*GP*AP*CP*CP*GP*GP*TP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*AP*(C34)P*CP*GP*GP*TP*CP*TP*C)-3'), ... (4 entities in total)
• Functional Keywords: n4-methylcytosine, restriction endonuclease, mcrbc, base flipping, dna binding protein
• Biological source: Escherichia coli; More
• Total number of polymer chains: 4
• Total formula weight: 46660.65

Authors

Sasnauskas, G. (deposition date: 2018-04-17, release date: 2018-09-19, Last modification date: 2024-01-17)

• Primary citation: Zagorskaite, E.,Manakova, E.,Sasnauskas, G.; Recognition of modified cytosine variants by the DNA-binding domain of methyl-directed endonuclease McrBC.; FEBS Lett., 592:3335-3345, 2018; PubMed: 30194838; DOI: 10.1002/1873-3468.13244

Experimental method

X-RAY DIFFRACTION (1.55 Å)