6GBM

Solution structure of FUS-RRM bound to stem-loop RNA

Summary for 6GBM

• Entry DOI: 10.2210/pdb6gbm/pdb
• NMR Information: BMRB: 34259
• Descriptor: RNA-binding protein FUS, RNA (5'-R(*GP*GP*CP*AP*GP*AP*UP*UP*AP*CP*AP*AP*UP*UP*CP*UP*AP*UP*UP*UP*GP*CP*C)-3') (2 entities in total)
• Functional Keywords: rna, rna recognition motif, rrm, rna binding protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 18575.86

Authors

Loughlin, F.E.,Allain, F.H.-T. (deposition date: 2018-04-15, release date: 2019-02-20, Last modification date: 2019-05-08)

• Primary citation: Loughlin, F.E.,Lukavsky, P.J.,Kazeeva, T.,Reber, S.,Hock, E.M.,Colombo, M.,Von Schroetter, C.,Pauli, P.,Clery, A.,Muhlemann, O.,Polymenidou, M.,Ruepp, M.D.,Allain, F.H.; The Solution Structure of FUS Bound to RNA Reveals a Bipartite Mode of RNA Recognition with Both Sequence and Shape Specificity.; Mol. Cell, 73:490-504.e6, 2019; PubMed: 30581145; DOI: 10.1016/j.molcel.2018.11.012

Experimental method

SOLUTION NMR