6G9V

Crystal structure of Aspergillus fumigatus UDP-N-acetylglucosamine pyrophosphorylase(AfUAP1) in complex with UDPGlcNAc, pyrophosphate and Mg2+

Summary for 6G9V

• Entry DOI: 10.2210/pdb6g9v/pdb
• Descriptor: UDP-N-acetylglucosamine pyrophosphorylase, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE, PYROPHOSPHATE, ... (5 entities in total)
• Functional Keywords: cell wall, anti fungal, pyrophosphorylase, aspergillus fumigatus, transferase
• Biological source: Aspergillus fumigatus Af293
• Total number of polymer chains: 2
• Total formula weight: 114396.81

Authors

Raimi, O.G.,Hurtado-Guerrero, R.,Borodin, V.,Urbaniak, M.,Ferguson, M.,van Aalten, D. (deposition date: 2018-04-11, release date: 2019-04-24, Last modification date: 2024-01-17)

• Primary citation: Raimi, O.G.,Hurtado-Guerrero, R.,Borodkin, V.,Ferenbach, A.,Urbaniak, M.D.,Ferguson, M.A.J.,van Aalten, D.M.F.; A mechanism-inspired UDP-N-acetylglucosamine pyrophosphorylase inhibitor; RSC Chem. Biol., 2020; DOI: 10.1039/C9CB00017H

Experimental method

X-RAY DIFFRACTION (1.75 Å)