6G9E

Crystal structure of immunomodulatory active chitinase from Trichuris suis - TsES1 - 6 molecules in ASU

Summary for 6G9E

• Entry DOI: 10.2210/pdb6g9e/pdb
• Descriptor: Immunomodulatory active chitinase, 1,2-ETHANEDIOL (3 entities in total)
• Functional Keywords: tses1, immunomodulatory potential, chitinase, eukaryotic protein expression, lexsy, secretion, dimer, intramolecular disulphide bridge, hydrolase
• Biological source: Trichuris suis (pig whipworm)
• Total number of polymer chains: 6
• Total formula weight: 333584.49

Authors

Malecki, P.H.,Balster, K.,Hartmann, S.,Weiss, M.S.,Heinemann, U. (deposition date: 2018-04-10, release date: 2019-04-24, Last modification date: 2024-01-31)

• Primary citation: Ebner, F.,Lindner, K.,Janek, K.,Niewienda, A.,Malecki, P.H.,Weiss, M.S.,Sutherland, T.E.,Heuser, A.,Kuhl, A.A.,Zentek, J.,Hofmann, A.,Hartmann, S.; A Helminth-Derived Chitinase Structurally Similar to Mammalian Chitinase Displays Immunomodulatory Properties in Inflammatory Lung Disease.; J Immunol Res, 2021:6234836-6234836, 2021; PubMed: 34869783; DOI: 10.1155/2021/6234836

Experimental method

X-RAY DIFFRACTION (2.69 Å)