6G8K

14-3-3sigma in complex with a S131beta3S mutated YAP pS127 phosphopeptide

Summary for 6G8K

• Entry DOI: 10.2210/pdb6g8k/pdb
• Related: 6g6x 6g8i 6g8j
• Descriptor: 14-3-3 protein sigma, ACE-ARG-ALA-HIS-SEP-SER-PRO-ALA-BSE-LEU-GLN, CHLORIDE ION, ... (6 entities in total)
• Functional Keywords: beta amino acid, hippo pathway, yap/taz, oncoprotein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 27836.30

Authors

Andrei, S.A.,Thijssen, V.,Brunsveld, L.,Ottmann, C.,Milroy, L.G. (deposition date: 2018-04-09, release date: 2019-04-17, Last modification date: 2024-01-17)

• Primary citation: Andrei, S.A.,Thijssen, V.,Brunsveld, L.,Ottmann, C.,Milroy, L.G.; A study on the effect of synthetic alpha-to-beta3-amino acid mutations on the binding of phosphopeptides to 14-3-3 proteins.; Chem.Commun.(Camb.), 55:14809-14812, 2019; PubMed: 31763628; DOI: 10.1039/c9cc07982c

Experimental method

X-RAY DIFFRACTION (1.25 Å)