6G8I

14-3-3sigma in complex with a R124beta3R mutated YAP pS127 phosphopeptide

Summary for 6G8I

Entry DOI	10.2210/pdb6g8i/pdb
Descriptor	14-3-3 protein sigma, ALA-HIS-SEP-SER-PRO-ALA-SER-LEU-GLN, CHLORIDE ION, ... (6 entities in total)
Functional Keywords	beta amino acid hippo pathway yap/taz, oncoprotein
Biological source	Homo sapiens (human) More
Total number of polymer chains	2
Total formula weight	27822.83
Authors	Andrei, S.A.,Thijssen, V.,Brunsveld, L.,Ottmann, C.,Milroy, L.G. (deposition date: 2018-04-09, release date: 2019-04-17, Last modification date: 2024-02-07)
Primary citation	Andrei, S.A.,Thijssen, V.,Brunsveld, L.,Ottmann, C.,Milroy, L.G. A study on the effect of synthetic alpha-to-beta3-amino acid mutations on the binding of phosphopeptides to 14-3-3 proteins. Chem.Commun.(Camb.), 55:14809-14812, 2019 Cited by PubMed: 31763628 DOI: 10.1039/c9cc07982c PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation