6G2T

human cardiac myosin binding protein C C1 Ig-domain bound to native cardiac thin filament

Summary for 6G2T

• Entry DOI: 10.2210/pdb6g2t/pdb
• EMDB information: 4346
• Descriptor: Actin, cytoplasmic 2, Myosin-binding protein C, cardiac-type, Tropomyosin (3 entities in total)
• Functional Keywords: cardiac thin filament regulator, contractile protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 16
• Total formula weight: 370146.14

Authors

Risi, C.,Belknap, B.,Forgacs, E.,Harris, S.P.,Schroder, G.F.,White, H.D.,Galkin, V.E. (deposition date: 2018-03-23, release date: 2018-10-17, Last modification date: 2018-12-19)

• Primary citation: Risi, C.,Belknap, B.,Forgacs-Lonart, E.,Harris, S.P.,Schroder, G.F.,White, H.D.,Galkin, V.E.; N-Terminal Domains of Cardiac Myosin Binding Protein C Cooperatively Activate the Thin Filament.; Structure, 26:1604-1611.e4, 2018; PubMed: 30270174; DOI: 10.1016/j.str.2018.08.007

Experimental method

ELECTRON MICROSCOPY (9 Å)